Before we explain how Tadalafil helps manage ED, we need to explain how erections occur naturally. When you become aroused, your body releases a substance called nitric oxide (NO). In turn, levels of a chemical known as cyclic guanosine monophosphate (cGMP) increase in your body, relaxing the muscles on the sides of your penis so blood can flow into the organ and trigger a stiff erection.
While all this is happening, your body also compresses the veins that take blood away from the penis, so that the blood remains in place and you can maintain that erection. Eventually, the PDE5 enzyme in your body gets to work, and it processes the cGMP. When that happens, your erection dissipates, and the penis becomes flaccid once again.
If you have ED, regardless of the underlying cause, this natural process is somehow interrupted. That makes it more difficult for you to get or maintain an erection that’s sufficient for intercourse. And that’s where Tadalafil, a PDE5 inhibitor, can help. By blocking this enzyme in your body, you’ll have an easier time getting an erection and holding on to it until sex is complete.
As mentioned earlier, ED can be caused by various factors, including:
For many people with ED, getting an ED medication like Tadalafil can be difficult enough that doctors still prescribe it to many thousands of people every year.
If you take any of the aforementioned medications, you’ll often get an ED medication that lasts for more than three hours, usually before sex. This can make it more difficult for you to get an ED medication that’s effective for that long if you’re really only taking one particular medication.
So, if you take one of the aforementioned medications every day and find that it’s not having any effect, you’re probably not getting an ED medication that works for you. And you’re probably not having an erection that’s sufficient for sex.
That’s where Tadalafil, or tadalafil derivatives, like Cialis, PDE5 inhibitors, and other PDE5 inhibitors come in. These PDE5 inhibitors work by blocking the enzyme that breaks down cGMP, which allows blood to flow more easily through the penis.
When that happens, that cGMP goes away, and you’re able to get an erection much earlier than you hoped for an otherwise impotentyth time.
If you’re really only taking one of the aforementioned medications, even a small amount could make it more difficult for you to get an ED medication that works for all of your ED symptoms without significantly increasing your risk of ED.
As we’ve already seen, PDE5 inhibitors work by blocking the PDE5 enzyme, which means that when cGMP comes in, it can help get blood away from the ED medication that you’re taking. That’s important, because that’s the only way to get an effective ED medication that all of a sudden get.
If that ED medication doesn’t work after a few hours of taking tadalafil, that means that you’re not really getting an effective ED medication that works all of a sudden.
If you find that your ED medication doesn’t get effective after a short time, you might well be taking an overdose of tadalafil that could be life-threatening.
That’s because that ED medication may not be having any effect on you, even if you’ve taken it every day since. That’s because taking a single dose of tadalafil may not work as well after three hours.
If you take one of the aforementioned medications every day and find that it’s not having any effect on you, it’s very likely that you’re not having an ED medication that works all of a sudden.
That’s probably why you’re experiencing the most bothersome symptoms of ED, because that’s where the PDE5 inhibitor and Tadalafil forms of these medications come in.
1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
Cialis, the popular prescription medication for managing both high blood pressure and low blood pressure, is available in Europe and is approved by the FDA for the treatment of erectile dysfunction (ED). The group's medical journal,Hypertension
However, recent studies have shown that daily Cialis use may vary among individuals.
The main side effects of daily use of Cialis include headache, facial flushing, indigestion, and blurred vision. These side effects are usually mild and subside after a short time. However, daily use may worsen side effects like ED, such as EDq.
If you suffer from ED, talk to your doctor about whether Cialis can help.Pharmacotherapy with Cialis
Orthostatic hypotension (a sudden drop in blood pressure when standing), a severe hypotension that may be fatal, or a sudden and worsening hypotension, may occur.
Before we explain how Tadalafil helps manage ED, we need to explain how erections occur naturally. When you become aroused, your body releases a substance called nitric oxide (NO). In turn, levels of a chemical known as cyclic guanosine monophosphate (cGMP) increase in your body, relaxing the muscles on the sides of your penis so blood can flow into the organ and trigger a stiff erection.
While all this is happening, your body also compresses the veins that take blood away from the penis, so that the blood remains in place and you can maintain that erection. Eventually, the PDE5 enzyme in your body gets to work, and it processes the cGMP. When that happens, your erection dissipates, and the penis becomes flaccid once again.
If you have ED, regardless of the underlying cause, this natural process is somehow interrupted. That makes it more difficult for you to get or maintain an erection that’s sufficient for intercourse. And that’s where Tadalafil, a PDE5 inhibitor, can help. By blocking this enzyme in your body, you’ll have an easier time getting an erection and holding on to it until sex is complete.
As we mentioned earlier, ED involves ED being caused by several factors. One of the factors that causes ED is heart disease, so the lack of sexual stimulation can contribute to the condition. And that’s where Tadalafil comes in. Tadalafil helps by relaxing the muscles in the sides of your penis, and by increasing the amount of cGMP that your body makes available. And that’s great because cGMP is necessary for erection by enhancing your lucky blood flow to the penis during sexual stimulation.
Now that you know how ED works, let’s take a closer look at how ED feels. And how it can feel.
Like other men, you may be surprised to learn that ED isn’t just a problem on the inside. It can be a whole host of different things, from stress to anxiety to physical intimacy to all these other things.
If you have difficulty getting an erection, talk to your doctor about ways to manage your ED. And of course, Tadalafil can also be an effective way to treat ED.If you find that Tadalafil doesn’t help, let your doctor know. They may increase your dose or prescribe a different medication. If you experience side effects or do not get an erection, they may contact your doctor for more information.
As you may already know, PDE5 inhibitors can lead to a condition calledpulmonasis.
is an oral medication that works by relaxing the muscles in the sides of your penis so blood can flow into the organ and trigger a stiffer erection. When that happens, the smooth muscle in your penis prepares to relax and produce blood that promotes erections.
When that happens, your body compresses the veins that take blood away from your penis, and you can get an erection. That’s very effective. And that’s great because your lucky blood flow is improving very fast. And because of this, you’re able to get an erection even if you’re not sexually aroused.
If you think you may have ED, you may be surprised to find that ED can be caused by a host of other factors, and Tadalafil can help. One of the ways that ED can be managed is by improving your sexual performance. And that’s especially important for men with ED, as that can impact their self-esteem and quality of life.
And that’s because ED can also affect a host of other things, too. When ED spreads, it can be called a medical emergency. That means that you need to get help right away if you have any of these symptoms:
If you think you may have ED, talk to your doctor. They may be able to make a more effective way to manage your condition.
Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.
You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.
There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-
• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).
• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets
for chest pain or use Rectogesic ointment?
• Nicorandil (Ikorel), used to treat angina
• Cimetidine, used to treat stomach or duodenal (peptic) ulcers
• Theophylline, used to treat asthma
• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin
• Anti-fungals such as itraconazole and ketoconazole
• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone
• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide
• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat
• Recreational drugs:- amyl nitrate (poppers)
If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.
Read available consultation questionnaireTadalafil is a prescription medication that is used to treat erectile dysfunction (ED) in men.
It is used to treat men with erectile dysfunction (ED) when a man cannot achieve an erection or has no ability to keep a hard, erect penis contraction.
Tadalafil works by helping to increase the amount of a man’s blood flow.
It is not given to men with prostate, kidney or bladder cancer.
Take Tadalafil as advised by your GP.
You should complete a short medical consultation questionnaire that asks for any tablets that can’t be taken with Tadalafil.
Some medicines, including other medications that you are taking to avoid interactions with Tadalafil, can be taken with Tadalafil. Some of these to avoid :-
If you are taking:
Siloxine (antibiotic) pills taken as needed to treat bacterial infections such as Roaccia, Cipro (ciprofloxacin), Zegerid, or Uti (uluacontinac).
Stade de France Pharmacy